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The verification of program integrity should be part of the evaluation of any behavioural intervention as lowered adherence to the protocol is often associated with poorer outcome [ 31].
Attempts to reduce or eliminate gap coverage may result in lowered adherence among the most vulnerable beneficiaries, leading to increased costs, poorer adherence and worse health outcomes.
GPs acknowledge that polypharmacy is a problem in their older patient population, especially because of the risk of adverse drug reactions, interactions and lowered adherence.
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Depressive symptoms can lower adherence and change in dietary studies.
This finding may be related to lower adherence or consultations with physicians.
Poor tolerability of oral quinine has been linked to lower adherence and subsequent treatment failures in patients [ 127– 127].
Increased pharmacy costs seemed to drive greater costs among highly-adherent patients, whereas lower adherence correlated to greater ER utilization but not to greater costs.
In M patients, this response is prevented by lower adherence.
Too short distances produce lower adherence due to overheating, resulting in internal stress inside the coating.
A lower adherence to bundles correlated with worsening clinical condition and higher mortality.
More importantly, lower adherence to medications is not associated with increases in medical service use.
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