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Thus, numerous "upper" pathways funnel into a small number of "lower" pathways.
Ring activation is followed by ring cleavage catalyzed by specialized dioxygenases (intra- and extradiol dioxygenases) that start the lower pathways.
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The results showed that both control strains TMB4511 and TMB4512 (i.e. the strain producing both XylB and XylC and the strain producing XylB, respectively) converted d-xylose to d-xylono-γ-lactone/d-xylonate at higher rates than all the strains containing genes from the lower pathway.
Prompted speech (e.g., following an authoritative script) can yield the recitation of valid proofs (lower pathway of Fig. 2), but we hypothesize that it does so without generating perceptuo-motor forms of knowing that are characteristic of intuitive understanding (e.g., Kellman & Massey, 2013; Kellman, Massey, & Son, 2010; Koedinger, Corbett, & Perfetti, 2012).
Group1 (better survival and lower pathway activity) contains frequent deletion of genes.
The MVA pathway can be divided into upper pathway and lower pathway, which are connected by mevalonate.
The lower pathway of γ-HCH degradation begins from 2,5-Dichlorohydroquinone (2,5-DCHQ) an intermediate of γ-HCH, which is mineralized by the lower pathway lin genes (linDER, linF, linGHIJ, and linKLMN) [ 6].
Second, the meta (also called lower) pathway encodes activities for the ensuing metabolism of 3 MBz into intermediates of the TCA cycle.
The lower pathway genes, including linGHIJ and linKLMN were found on chromosomes 2 and 1, respectively, in regions that were conserved among sphingomonads [ 19].
Among all the lin genes of the lower pathway, linF was the most highly conserved, as its amino acid sequence was 100% identical in all genomes.
The enzymes encoded by pcpA and pcpE likely existed as part of a standard lower pathway for degradation of naturally occurring compounds.
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