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This is also reflected in the lower overlap between the two independent data sets (Table 1).
While this manuscript was in preparation, a study has revealed that TFs with more similar TF paralogs had lower overlap between their binding and knockout targets [ 21].
The context mining based method gave significantly lower overlap between gene sets than ISA, thus using gene sets from the context mining based method will have less chance of inferring undesirable generic interactions between similar gene sets.
Examining the results in further detail, the lower overlap between the brain's correlate of shutdown dissociation and PTSD symptom severity for neutral stimuli suggest a qualitatively differential modulation of the processing for the two clinical syndromes.
Strikingly, a significantly higher overlap was found between genes downregulated by PTZ and genes upregulated in DS, and a significantly lower overlap between downregulated genes in PTZ and DS sets.
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Finally, we found a negative relationship between niche overlap and specificity, with more specialised phages tending to exhibit lower overlap (Figure 4).
As found above with holoTC the confidence intervals of the upper and lower limits overlap between the different groups.
Thus, as per the hypothesis of reduced redundancy [28], sparsely represented ganglion cell sub-populations have lower degrees of overlap between adjacent receptive fields than more abundant sub-populations, and may demonstrate identifiable functional loss earlier.
Although many repetitive element regions are distinctive enough to permit unique mapping of 35 or 50 bp sequence reads, underrepresentation of repetitive elements in the "mappable" genome may also contribute to the lower than expected overlap between DMEs and several repeat classes.
However convergence between the GPBMs and the disinhibited eating factor was on the low side indicating a lower level of overlap between the constructs.
Fully 69% of all responders reported having had at least one worsened or newly incident respiratory symptom while performing WTC response work (63% upper airway and 47% lower airway symptoms, with overlap between the groups) (Table 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com