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The aim of this study was to compare the wear of fixed-bearing total knee replacements with curved and flat inserts and to test the hypothesis that the flat inserts which give higher contact stresses and smaller contact areas would lead to lower levels of surface wear.
Primary human Kupffer cells were found to display heterogeneous expression of M1 and M2 markers, and Kupffer cells expressing higher levels of M2 markers (CD163) take up significantly more nanoparticles than Kupffer cells expressing lower levels of surface CD163.
Lower levels of surface FcεRI consequently render immune cells less sensitive to allergen stimuli [31].
In addition, TCR signaling leads to lower levels of surface CD8 molecules [23], [25], [26].
In 2 µM lovastatin treated cells for 24 hrs, lower levels of surface expression of VEGFR were evident.
Flow cytometric analysis showed that DCs, defined as ClassII+CD11c+, from IFNAR1−/− had lower levels of surface expression of CD40 co-stimulatory molecules than wild-type controls (Figure 1C).
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This is supported by our acoustic microscope results which show a lower level of surface damage in the nanocomposites after a given lapping or polishing process.
Thus, older stars such as the Sun have a much slower rate of rotation and a lower level of surface activity.
Analysis of CD33 and CD45 surface expression of all samples within this AML cohort defined three patient samples with two distinguishable leukemic cell subpopulations, referred to as Blast 1 and Blast 2. In all cases, Blast 1 was defined as a cell subset with higher CD33 and CD45 levels, whereas Blast 2 cells had lower levels of these surface proteins.
Class Ib genes encode proteins structurally similar to class Ia but usually displaying limited tissue distribution, low polymorphism, and relatively lower levels of cell surface expression (Gleimer and Parham, 2003; Hofstetter et al., 2011).
In particular, the collagen fibrils were more clearly visible, suggesting that lower levels of fibril surface-associated proteins were decorating individual collagen fibrils (supplementary material Fig. S3).
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