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However, it is fair to note that when considering regions identified at lower levels of statistical stringency (FPR > 50%), we frequently observed regions of high differentiation within 2 5 cM of each other in two different populations (table 1 and supplementary table S2, Supplementary Material online).
However, the lowering of the stringency levels of selection means genes with a lower level of expression variation are also chosen.
We were also able to detect 31 underexpressed genes in invasive carcinomas when compared with DCIS, but only when the stringency of the statistical comparison was dropped to within the 95% confidence interval (i.e. P < 0.05), reflecting a lower level of consistency in these gene expression changes when comparing DCIS with IDC (Fig. 4).
Their growth requires lower levels of hormone.
Lower levels of distress.
However, these effects turn negative once the level of stringency leaps over a certain threshold.
At this level of stringency, we identified D-D fusion in ~2% of the productive TCRβ rearrangements.
To increase the level of stringency, GO-IEA terms were discarded.
The level of stringency applied when determining the cutoff value influences the prevalence rates.
It was not clear as well the level of stringency used in the analysis.
However, this results depends on the level of stringency for defining consensus modules.
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