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In addition, D- and L-diastereomeric peptides exhibited lower interaction with zwitterionic eukaryotic membrane and showed the significant membrane damaging effect to bacterial cells.
The density functional theory (DFT) calculations reveal that FeN2 outperforms FeN4 due to its lower interaction with *O2 and *OH intermediates and enhanced electron transport, however, achieving an optimum design of these earth-abundant materials with the enriched FeN2 catalytic centers is still a great challenge.
This experiment demonstrated that Ms2Yah animals had a lower interaction with new congeners.
Pre-aggregation resulted in a strong and specific binding of A β-L34V to DR4 and a lower interaction with DR5.
Anti-glycan IgG antibodies showed lower interaction with the glycans (ascites (8.11 × 10 RFU), plasma (9.80 × 10 RFU) as well as anti-glycan IgA (ascites (8.8 × 10 RFU), plasma (10.4 × 10 RFU)).
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This polymer had lower interactions with blood components than the unmodified PEI.
The results showed that the diblock copolymer-based polyplexes showed lower interactions with serum proteins, lower cellular uptake and very low gene expression in both Hep G2 and Hela cells in comparison to statistical copolymers.
The predominant characteristics of these copolymers that have been reported include solubilization of hydrophobic drugs, sustained release, selective targeting, and lower interactions with the RES [ 2, 4, 5].
In order to lower interactions with the extracellular matrix, we created BMP2 ligands lacking the heparin binding sites (so-called coreBMP2 variants, see Methods section).
The absence of heat shock transcription factor in the networks is due to its lower interaction value with other genes than threshold.
The docking experiment showed that all mutants had a suitable pattern of interactions, with similar or lower interaction energies compared with the native protein.
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