ID, epilepsy and ASD diagnosis were each associated with lower FA values, demonstrating additive effects.
Lower FA and higher MD indicate reduced fiber density, increased membrane permeability and/or increased structural disorganization.
Results of that study showed that cocaine-dependent subjects had lower FA in several brain regions including the corpus callosum and superior longitudinal fasciculus.
Results of that study showed that the cocaine-dependent subjects had significantly lower FA in the frontal white matter compared with the controls.
We estimated distributions using bootstrapping and calculated half-life and asymptote of the fitted curves.TSC was associated with a lower callosal fractional anisotropy (FA) than ASD, and ASD with a lower FA than HC.
Patient group had lower FA values at corpus callosum, bilateral inferior frontooccipital fasciculus (IFO), bilateral inferior longitudinal fasciculus (ILF) and left superior longitudinal fasciculus (SLF) compared to controls (p<0.05).
Findings of lower FA in patients with schizophrenia likely reflect two inversely related signals: reduced density of principal axis fiber tracts and increased off-axis diffusion sources.
Habitat loss was associated with higher FA in males only while the habitats with low degree of configuration tended to be related to lower FA in adults only.
There was also a significant relationship between FA, radial diffusivity, and impaired decision making, such that subjects with evidence of impaired IGT performance exhibited lower FA and higher radial diffusivity.
For dMRI, SZ shows lower FA values than HC in major white matter tracts (orange arrows) including forceps major (FMAJ), forceps minor (FMIN 35, SLF36, and ATR37, which can potentially connect the identified brain regions in GM or fALFF.
Whole-brain, voxelwise analysis of FA showed that cocaine-dependent subjects had lower FA and higher radial diffusivity in both frontal and parietal white-matter regions, as well as the corpus callosum.
