The frequency of side effects, lower effectiveness in chronic infections, and logistical difficulty for physicians wishing to prescribe these drugs create barriers to successful treatment of patients with Chagas disease.
Mr. Graedon and the lab conjecture that the different dissolution rates might be to blame for the reported side effects and lower effectiveness of Budeprion.
The lack of effect we observed may therefore reflect this lower effectiveness of human KP-10 in mice.
The DBTs with little or no steric hindrance effect, and thus with high intrinsic reactivities, had lower effectiveness factors, indicating a stronger intra-particle diffusion resistance.
SO selective effect on GBM CSCs is corroborated by the lower effectiveness of SO on GBM differentiated cells compared with the same cultures maintained in "stem-permissive" conditions.
Helmets were effective in reducing injury in both helmet law settings; lower effectiveness estimates were observed in universal law states.
But how can this explain lower effectiveness ratings for the most charismatic?
One reason for this unusually intense flu season is probably the vaccine's lower effectiveness against the predominant strain.
The cold traps presently used have lower effectiveness and get plugged prematurely.
Still, even with lower effectiveness against H3N2, "I would still take 25percentt over nothing any day of the week," Belongia said.
Studies with live-attenuated influenza vaccine (FluMist) showed similar findings (though the FluMist is not recommended this year because of concerns of lower effectiveness).
