Sentence examples for lower compound from inspiring English sources
A number of therapies for complex diseases use combinations of drugs that allow targeting of multiple mechanisms and allow therapeutic efficacy at lower compound concentrations, limiting toxicity of single agents.
For all proteins evaluated, the observed expression changes occurred at lower compound concentrations in parental cells compared to resistant cells.
Fruit kept at 4 °C for 6 and 12 days and then restored at 22 °C were characterized by a different volatile profile, not only determined only by overall lower compound concentration but also by an increased production of off flavours (Fig. 6).
Nevertheless, some structure-specific interactions observed among native N-carbamoylase molecules may promote multilayer adsorption and thus lead to a much higher adsorption capacity, 715 nmol/g gel and a lower compounded binding affinity, 0.42 μM−1.
Simvastatin is an important cholesterol lowering compound and is currently synthesized from the natural product lovastatin via multistep chemical synthesis.
Interestingly, although atorvastatin is a more potent cholesterol lowering compound than simvastatin [41], in our study both simvastatin and atorvastatin showed an equal association with low values of periodontal inflammatory burden index PIBI.
A modest increase in the serum gastrin level in adult patients under a long-term treatment with acid-lowering compounds, especially PPI, has been reported [6].
Several selective thyromimetics have been shown to be useful lipid-lowering compounds in animal studies [6], [7], [8] resulting in clinical trials [9].
The effect of screen-selected cholesterol lowering compounds on the major sterol pathways was studied in CT60 mutant CHO cells lacking NPC1 protein.
In the work presented herein the mechanisms by which screen-selected sterol-lowering compounds reduce cholesterol levels in the LSOs in cultured NPC1 cellscells were examined.
Experiments showed that the active lipid-lowering compounds are triterpenoids.
