Cartilage tissue strands had higher cellularity, while native cartilage had relatively lower cell density and a higher ratio of ECM.
This could be a result of the initial lower cell density used on the 2D substrate (i.e., 1 500 vs. 50 000 cells/well), which provided more surface area for cell proliferation before reaching confluency.
Kin discrimination can manifest as an apparent demarcation line (a region lacking cells or with much lower cell density) between antagonist strains swarming toward each other.
But small colony variant exhibited a lower cell density that is 4.5 log fold lower than that attained by wild type (Fig. 4), proving that plasmid confers growth advantage both in vitro and in vivo and its absence results in reduced growth.
MC3T3-E1 osteoprogenitor cells cultured on fiber surfaces in the absence of osteogenic factors exhibited a lower cell density after 7 and 14 days of culture than cells cultured on spin-coated surfaces, but cell density increased with fiber diameter.
An increased proliferation rate of the cells grown on pNIPAM-azide surfaces and a lower cell density on pNIPAM-maleimide surfaces compared to the pNIPAM surfaces was observed, which can direct their use to potential surfaces in regenerative medicine approaches.
Area (a) has a lower cell density than area (b), indicating the heterogeneity of the tumor components.
Therefore, the lower ALP activity and calcium deposition on all scaffold materials might be due to the lower cell density during the culture compared to TCP.
Worse homogeneity of VSMCs growth and lower cell density (see Figure 6) are observed on the sample sputtered at 40 mA for 150 s.
However, lower cell density, longer fermentation time, and lower comprehensive titer of AC and 2,3-BD were observed after slaC inactivation.
As shown in Table 1, the strain constitutively expressing the flocculent phenotype reached a lower cell density that the inducible strain, with the latter showing comparable growth values to those displayed by the wild-type strain.
