Sentence examples for low-quality trials from inspiring English sources

Main Outcome Measures: For the scales allowing classification into high- and low-quality trials, a rating system with 4 levels of evidence was used to summarize conclusions drawn.

Considering that low-quality trials are more likely to overestimate efficacy, it is not surprising that 75% of the 20 RCTs, which we identified as poor in our review, generated positive results, as compared with 63.6% in the other 11 higher-quality trials (that is, whose quality score was larger than 2).

Exclusion of low-quality trials may thus directly impact our clinical practise.

Low-quality trials are more likely to overestimate the effect size [ 41, 42].

Furthermore, high- and low-quality trials were grouped separately in the meta-analyses for easy comparisons.

The outcome of a domain-based assessment demonstrated that there are a number of low-quality trials.

The effect of study quality on MV did not show any significant effect, although one low-quality trial [ 16] explored this outcome.

When evaluating clinical response, a significant benefit was demonstrated with amikacin/ceftazidime versus pefloxacin/ceftazidime, risk difference (RD) = 20%9595% CI, 4 36%), in a single low-quality trial.

They looked for an effect in both the smaller, low quality trials and in larger, higher quality trials.

Homeopathic remedies were more likely to have had a positive effect in the small, low quality trials.

These estimates are likely to vary substantially according to the age of the subjects, with vaccine efficacy decreasing significantly with the increase of the mean age of the patients, and to the methodological quality of trials, with low quality trials associated with an overestimation of influenza vaccine efficacy.