Although preclinical studies historically have helped inform early trial development of combination therapies, the contributory value of phase II trials and ultimate success in identifying agents with a survival impact in phase III trials has been reported to be low, warranting new methodologies [ 3].
The complex nature of flow about the blades in low Re warrants for a careful and 'clever' selection of the airfoil profiles in the SWT design process [7].
Finally, we recommend that the shift to second-line ART might be too low and warrants close monitoring.
Slide-positive RDT-negative severe illness represents patients with low parasitemia warrants diagnosis and treatment of other, possibly HIV-related, alternative illnesses [ 14, 46, 47].
Because acquisition of a survival advantage is crucial for the development of cancer (Hanahan and Weinberg 2000), long-term exposure to arsenite, even at low doses, warrants concern.
"Yields are fair or, in our view, a little too low" to warrant buying, said Mike Martino, who helps manage $70 billion at Putnam Investments in Boston.
Its assessment of poppers has consistently been that although they can cause health harms, the frequency and severity of these are too low to warrant control under the Misuse of Drugs Act 1971.
All but daring Democrats to follow through, Republicans insisted Ms. Millett's nomination was not justifiable given the court's workload, which they argue is too low to warrant another judge.
About 45 percent of 1,080 children in three Fukushima communities surveyed in late March tested positive for thyroid exposure to radiation, according to a recent announcement by the government, which added that the levels were too low to warrant further examination.
The low incidence warranted a rather conservative prevention policy.
