Sentence examples for low trail from inspiring English sources

Because we found high OPG/TRAIL ratio associated with risk of rapid erosion progression mainly due to low TRAIL values, our results favor a protective effect of TRAIL on bone erosion in RA.

Accordingly, silencing of c-FLIP alone was sufficient to restore TRAIL sensitivity to similar extent as cells exposed to a HS, even at low TRAIL concentrations.

Specifically, respondents preferred dense trailside shrub vegetation and low trail user numbers and disliked viewscapes showing city buildings and removal of most ash trees.

Of note, low TRAIL levels at the patient discharge were associated with increased incidence of cardiac death and heart failure in the 12-month follow-up, even after adjustment for demographic and clinical risk parameters (hazard ratio [HR] of 0.93 [95% CI, 0.89 to 0.97]; p = 0.001).

This is in keeping with the constitutive, but relatively low, TRAIL expression shown in Figures 3a and 5c.

The absence of macroscopic toxicity using low TRAIL concentrations (25 mg kg−1) is encouraging for further bioactivity and pharmacokinetic studies to implement present findings.

For instance, in renal cell carcinoma high TRAIL-R2 and low TRAIL-R4 expression correlated with poorer overall survival [ 21].

U87MG and U118MG cells displayed low TRAIL-R1 levels in line with a recent study reporting frequent epigenetic silencing of TRAIL-R1 in glioblastoma.

To test the effect of ATO on TRAIL sensitivity of these tumour cells, for each cell line the lowest TRAIL concentration that caused 10 20% cell death was determined.

Real Time RT-PCR assays revealed that while TRAIL-R2 expression was the highest on transcript levels, TRAIL-R4 decoy receptor expression was the lowest TRAIL receptor expressed in MDA-MB-231 breast cancer cells.

Moreover, novel quantitative Real Time RT-PCR assays suggested that while the level of TRAIL Decoy Receptor-4 (TRAIL-R4) expression was the highest in MCF7 cells, it was the lowest TRAIL receptor expressed in MDA-MB-231 cells.