Sentence examples for low systemic from inspiring English sources

In two Phase I studies, the PARI system generated small amikacin fosfomycin droplets and achieved high tracheal aspirate concentrations with low systemic exposure [64 66].

The therapeutic efficacy of lipophilic drugs is commonly restricted by the low systemic exposure after oral administration.

The insertion of these sites controlling E1A-Δ24 results in a low systemic toxicity profile in mice.

Due to the 'uterine first-pass effect', hormones concentrate in the uterus and nearby tissues with low systemic exposure.

Negligible to very low systemic estradiol absorption was observed whether given at 4, 10, or 25 μg.

Low systemic exposure to parent yakuchinone A was observed.

Our findings asserted the hypothesis of low systemic diffusion of inhaled colistin.

The patient showed low systemic vascular resistance hypotension during off-pump single-lung transplantation.

Thus, the inhaled route may offer the benefit of an effective alveolar penetration with a low systemic diffusion [6].

These dosages could preferentially assert our clinical and biological results of the low systemic diffusion of the inhaled route.

This low systemic exposure can provide a potential tool to differentiate topical (lung) vs systemic efficacy and side effects.