Taking the poor bioavailability and low stability of curcumin into account, we asked the question whether the degradation products contribute to the observed inhibition for these enzymes.
However, recent articles have described problems associated with the low stability of some TMS derivatives.
The short half-life and low stability of ROS further increase the technical demands.
However, their applications have been limited due to transient translation and relatively low stability of cmRNAs compared to DNA.
However, the low solubility and low stability of pentacene in common organic solvents have hindered its applications.
In turn, the low stability of the dimers formed by K721A-EGFR is consistent with the key role played in stabilising dimer interfaces by the opening and closing of the ATP-binding site during ATP hydrolysis56.
The low stability of the intermediate allows a large free-energy gain upon trimerization, which serves as driving force for rapid assembly.
However, the high overpotential, sluggish reaction dynamics and low stability of electrode materials are the main barriers in developing an excellent catalyst for the anodic electro-oxidation process.
However, some challenges still persist due to the lack of motivation for recycling and the problem of the limited usability (or low stability) of many of the end-products.
Additionally, the low stability of heme-containing peroxidases to hydrogen peroxide, the low reaction rates of laccases, the mediators toxicity, the limited availability and high costs of these enzymes are other limitations detected for commercial applications.
The low stability of ZnS nanoparticles within oxic and complex environments such as the studied soil was the key explanation for the radical change in pig slurry-borne Zn speciation after long-term amendments.
