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Matrix and polymerase viral genes, which show a low rate of variation, were chosen to design amplification assays to ensure that any genotype of the human metapneumovirus could be detected.
From the explanation given regarding these five SCs, we can conclude that the SCs with a low rate of variation do not result in a change in the power of the first detail, which is found in the frequency band 41.67 83 mHz.
As well, homoplasy is unlikely, given the low rate of variation of angiosperm and conifer mitochondrial introns [ 47, 49].
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This confirms the extremely low rate of accumulation of variation that characterizes M. tuberculosis, which is approximately 3 times and 44 times slower than that observed in Escherichia coli and Staphylococcus aureus, respectively [ 37].
An important consequence of the low frequency of slender cells in chronic infections is a low rate of productive antigen variation, since intermediate and stumpy forms do not replicate (Reuner et al., 1997) and cannot contribute to new populations of antigenic variants.
The intron and exon of trnL show few nucleotides changes within Fagaceae family, particularly among the Castanea and Quercus genera according to the low rate of chloroplast DNA variation within this family, as previously shown for other cpDNA regions by several authors [ 7, 38- 40].
This result was expected, since SNPs&GO was tuned to have a very low rate of false positives (variations predicted as disease but observed as neutral) at expenses of the coverage (some disease related variations are discharged as neutral).
Low rates of sequence variation at the ASGR, therefore, suggest that the ASGR might be of recent origin.
With such a low rate of genetic exchange, the strains accumulate sequence variation by mutation and thus genetically diverge.
Environmental factors, such as seasonal variations, might contribute to a low rate of PCP in Africa.
The most likely explanation of low levels of mtDNA variation within coral species, then, is a low rate of nucleotide substitution.
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