Sentence examples for low predisposition from inspiring English sources

This argument needs, in our opinion, further evaluation to specify if the prevalent presence of aura characterizes a migraine phenotype with low predisposition to chronic pain.

Similar to the ceramide composition, no specific epidermal lipid composition was detected in body sites with high predisposition for atopic lesions compared to sites with low predisposition for atopic lesions.

In individuals with low predisposition to atherosclerosis the mean level of C3256T heteroplasmy was 16.8%, as compared to 23.8% in moderately predisposed subjects and further to 25.2% and 28.3% in significantly and highly predisposed subjects, respectively [ 28].

Other, less frequent tumor types observed in DKO mice included low grade intestinal adenomas (5%) and malignant teratomas (7.5%), to which 129Sv mice have a modest predisposition [21].

It has been suggested in cell studies that inherited G2 chromosomal radiosensitivity in few individuals is a marker for low penetrance predisposition to common cancers such as breast cancer and colorectal cancer (Baria et al, 2001).

We previously found that 40% of breast cancer patients showed enhanced sensitivity to X-ray induced chromosome damage in G 2 lymphocytes and suggested that this might indicate a low penetrance predisposition to breast cancer, for which there is good epidemiological evidence.

In this context, we cannot exclude that the mutated G691S RET allele, over-represented in the epithelial radiation-associated tumours compared to controls, may lie in linkage disequilibrium with other sequences that may confer low level predisposition to or protection against anarchic growth of C-cells.

A gene thought to be involved in low-level predisposition to the disease is ERBB2 (HERBB2

EMSY (C11orf30) is a novel gene that could be involved in low-level predisposition to breast and ovarian cancer [ 11].

To create a resource for identifying low-penetrance predisposition alleles for CRC, we established the National Study of Colorectal Cancer Genetics (NSCCG) in March 2003 to collect DNA and clinicopathological data from 20 000 cases.

We proposed that enhanced sensitivity to G 2 or G 0 irradiation was a marker of low-penetrance predisposition to breast cancer, and have recently demonstrated heritability of sensitivity in families of breast cancer cases.