As a matter of fact, variability could be introduced by 454-sequencing [ 39] and PCR amplification; in particular, errors produced in the early PCR cycles could then be spread in multiple reads with a low possibility to distinguish them from real SNCs.
The taxonomic composition inferred by the 454 amplicon sequencing with our non-degenerate universal primer set correlated well with that obtained by Illumina metagenomic sequencing, indicating that our universal primers can characterize microbial communities without substantial bias and with low possibility to amplify eukaryotic rRNA genes.
Profiling of CYP450 and hERG channel inhibitory effects for the active compounds revealed their low possibilities to exhibit undesirable drug drug interactions and cardiac side effects.
On the one hand, he (1962 [1846]) condemned aspects of his contemporary social world, claiming that many people have come to function as merely place-holders in a society that constantly levels down possibilities to the lowest common denominator.
The treatment volume was reduced to 40 Gy for cases with a low possibility of tumour extension to adjacent structures, such as the ethmoid sinus or orbita.
Biological treatment process of phenolic compounds has been proven to be more cost effective, practical, and highly reliable as it leads to low possibility of by-product formation.
If a high inconsistency (low possibility) is detected, it is possible to investigate what is causing it, and thus correct the measurements or improve the model.
Based on measurements of aerodynamic drag and lift coefficients and by a verification of Glauert den Hartog criterion, it could be concluded that is a very low possibility for EC model to encounter galloping; for extremely high wind speeds though, this might not be impossible.
Consequently, our finding of no significant difference between ASEs and CSEs regarding sdSNPs suggests only a low possibility that sdSNPs lead to the generation of new exons.
Compared with HPLC, the EIA methodology does not need cleaning steps (removal of interfering compounds), thereby simplifying the analysis and shortening its time course, besides its high specificity, low cost, and possibility to use small samples.
Diagnosis of PTB in pediatric population represents a challenge due to nonspecific nature of its signs and symptoms and to the low possibility of identification of Mycobacterium tuberculosis, as we found in this series of cases (only in 30.4%).
