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Exact(13)
Due to the low population frequency of the more recently described G2677A allele (<2% in Caucasians), this variant was not genotyped in the present study [28].
This divergence could be related to specific population genetic background or to random chance in our results due to low population frequency.
One of the alleles at each polymorphic site composing the significant haplotype had a low population frequency (pC = 0.08 for C871G; pT = 0.06 for C1177T), and was associated with short lifespan (Table 3).
Further evaluation of the known polymorphisms revealed a low population frequency for 4 of them.
All the SCL alleles with extreme number of codons added or predicted under nonstop decay have low population frequency.
A neutral mutation will take many generations until the mutated allele reaches a high or low population frequency.
Similar(47)
The absence of GalileoN insertions in the analyzed non-inverted chromosomes should be no surprise because insertions of actively transposing families are expected to be present at low population frequencies under transposition-selection balance [77], [78] and we sampled just a few non-inverted chromosomes.
This is constituted by other non-synonymous changes, often defined as "private" or "almost private" mutations, which because of their very low population frequencies are not (yet) reported in any of the currently available databases for mtDNA variation, and for which a functional role in some cases is not unlikely.
The insertions we observed occur at low population frequencies, and reduce Hsp83 gene expression.
That a selective sweep can also amplify new diversity at very low population frequencies is thereby often overlooked.
The models predicted that most Drosophila TEs should be found at low population frequencies at their insertion sites.
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