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This may indicate that H5N1, in its current form, poses a relatively low pandemic risk.
However, these mutations appear unstable, suggesting low pandemic potential of H5N1 in its current form.
The pandemic season 2009-2010 represented a challenge for vaccine effectiveness studies due to the availability of the vaccine after the pandemic peak and the low pandemic influenza vaccination coverage.
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Thus, for example, residents of rural areas were relatively unlikely to be exposed to novel strains of bacteria while recovering from influenza, and they had low pandemic-related mortality rates.
The results also show that in a low fatality pandemic a pre-pandemic vaccine might result in savings of 0.13-0.260.13-0.26% domestic product, and a matched vaccine could result in savings of 0.26-0.51% for a single dose and 0.49-0.96% for a double dose.
As noted in the main text, during past screening initiatives the absolute number of infected travellers was very low: for pandemic influenza A/H1N1 only 45 and 69 cases were imported in to Sydney and Auckland, respectively (Hale et al., 2012; Gunaratnam et al., 2014).
Our study revealed a low (21.1%) pandemic influenza A/H1N1 vaccination rate among children whose parents are healthcare workers.
The absolute risk for HCC development in patients with DM2 and obesity can be considered low; however, the pandemic of these two diseases can transform this small number into a great number of HCC cases.
The divergent kinetic effects occurred mostly at early time-points (between days 1 and 2 post-infection), and we observed analogous kinetic effects with different doses of low pathogenicity 2009 pandemic H1N1 influenza virus (CA04-WT).
Phase 1: the lowest level of pandemic alert; indicates that an influenza virus, either newly emerged or previously existing, is circulating among animals.
A pre-pandemic vaccine with moderate efficacy and 60% coverage could result in large relative savings for any low or high fatality pandemic of £2.2bn-£10.8bn, or £20.2bn-£39.0bn for extreme scenarios.
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