Sentence examples for low levels of modification from inspiring English sources

A cell-based SUMOylation assay was optimized to visualize and quantify SUMO modification, which for endogenous proteins, is a highly dynamic process, and only low levels of modification are typically observed for an individual protein at any given time (Johnson, 2004).

After adjusting the curative recipe, the modulus and tensile strength and abrasion resistance of the SBR/MSO vulcanizates with low level of modification were tremendously improved with the tensile strength and elongation at break being significantly higher than that of SBR/NO vulcanizate.

Despite the low level of modification of individual sites within the protein population, low-level modifications can have significant signaling and other bioactive effects on a system.

Inefficient or aberrant operation of these processes often results in low levels of gene modification or undesired sequence changes [5].

We were unable to identify significant differences in the length of intergenic regions containing group1 and 2 ARSs when compared to later firing ARSs (Fig. S6B, W = 1817, P-value = 0.66) We conclude therefore that non-telomeric late origins are enriched in K36me3 compared to early firing origins, which show particularly low levels of this modification.

a-7-KetoChol gave no evidence of HSA adduction while a-CholEp afforded relatively low levels of protein modification.

Thus, these techniques for the most part require application of radioactively labeled carcinogens and the use of relatively large amounts of DNA for analysis at low levels of DNA modification.

Immunohistochemical staining for the repressive chromatin modifications H3K9me2 and H3K27me3 revealed low levels of these modifications in CIS cells, whereas Sertoli cells in CIS-containing tubules showed high levels of both modifications.

Finally, cluster 4, which represents maximum numbers of genes, has low levels of histone modifications.

This method has the advantage that low levels of DNA modifications, approximately 1 modified base per 10 5) nucleotides, can be detected.

Low levels of this DNA modification have been detected by some methodologies (Dunwell et al. 2013; Capuano et al. 2014; Takayama et al. 2014) but not by others (Zemach et al. 2010; Raddatz et al. 2013).