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These items were designed to measure activities across a wide range of functional independence levels to enable the detection of functional changes in individuals with both high and low levels of functioning [ 28].
This study examined the levels of distress and impairment in over 1,600 individuals presenting to youth mental health services with a primary diagnosis of UP or BD and explored which combination of demographic, clinical and substance use parameters identified cases with high or low levels of distress and/or high or low levels of functioning.
The authors conclude that low levels of functioning p53 in HPV/p16-positive cells could be activated by radiotherapy, leading to cell death and providing evidence for enhanced radiosensitivity in HPV/p16-positive cells [ 35].
Across the whole study sample, the poverty of resources is one of the key factors associated with high levels of illness severity and low levels of functioning and social outcomes (particularly those measured by the Honos) at follow-up.
To address this measurement gap, we created two custom parent-proxy physical functioning short forms for use among children at risk for low levels of functioning, using pediatric Patient Reported Outcomes Measurement Information System (PROMIS) item banks for Upper Extremity and Mobility.
These children showed very low levels of functioning: a mean IQ of 37.1 was found [ 43].
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In this relatively small study of 20 patients, emphasis was placed upon maintaining function in demanding workplace settings rather than accepting the necessity of at best a relatively low level of functioning.
The so-called "Jack-of-all-trades" effect in European forests generates a low level of functioning in highly diverse forest stands (Van der Plas 2016b).
Therefore the P5 indicates the cut-off for a low level of functioning.
For ADL, the 4 lowest scores (i.e. 3 – 6) are considered as a relatively low level of functioning (category '-').
Additionally, patients with a low level of functioning (below 45 on at least one of the GAF scales) and a minimum of 2 needs in the domains of accommodation, welfare benefits, alcohol and drugs, were classified as SMI patients [ 33].
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