The ores were low-grade, often varied in content, and were difficult to refine.
Pro-coagulability and low grade inflammation, often seen in chronic hyperglycemia, can induce insulin resistance [ 46].
In contrast, low grade gliomas often do not show amplification of tyrosine kinase receptors [ 16], but are also invasive.
Lastly, salvage chemotherapy followed by autologous HSCT may not be the optimal treatment strategy in high-risk transformed FL as it may eradicate the high grade component of the lymphoma, but the low grade component often recurs.
Primary glioblastomas arise without a preceding low grade glioma, often show amplification of epidermal growth factor receptor (EGFR) and murine double minute 2 (MDM2), along with inactivation of phosphatase and tensin homolog (PTEN) and p16 tumor suppressor genes.
A more sensitive work-up for myocardial inflammation should be undertaken using highly sensitive immunohistological techniques for the detection of the low grade inflammation often seen in the chronic phase of disease consistent with inflammatory cardiomyopathy (DCMi) [ 56].
The same could apply to our population as well, considering that a low grade inflammation often coexists with T2DM and obesity and that in our study we did not recognize differences between acute and stable condition of CAD.
However, a substantial amount of research has been dedicated to conventional heat integration where low grade heat is often ignored.
A large amount of low grade energy is often wasted without heat recovery in the process industry.
One criterion for the validity of arthroscopic diagnosis is the "inter-observer-validity". The diagnosis of deep cartilage defects has high validity but the diagnosis of low grade lesions is often inaccurate [ 6- 11].
Tumours diagnosed in the most recent cohort were smaller, more often lymph node negative, and more often low grade than tumours from the first time period.
