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It has a low endpoint value (blue color) compared to the nearby compounds (red color).
It has a relatively low endpoint value of -6.35, and is therefore drawn in blue.
It attracted our attention in CheS-Mapper, as it has a relatively low endpoint value (and is therefore colored in blue), but is spatially close to compounds with high endpoint values (colored in red).
In contrast to ES5, the ES1 immunogen required three inoculations to elicit very low, but detectable responses directed toward the 2F5 epitope and displayed low endpoint titers of 1,250.
* These results were interpreted as negative by the Xpert® assay but had typical amplification curves with a high cycle threshold and low endpoint.
In addition, both C. thermocellum strains had low endpoint fermentation yields and this may be in part be due to carbon flow through alternate pathways.
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During our evaluation of this assay, we noticed typical amplification curves for some specimens that had high cycle thresholds and low endpoints, which were interpreted as negative by the Xpert® assay.
We noted typical amplification curves with high tcdB cycle thresholds (Ct) and low endpoints (Ept) that are labeled negative by the Xpert® C. difficile assay (Cepheid) and undertook this study to determine their significance.
Thereafter, a comparison of effect values, regardless of the causative mechanisms, should be made, firstly to determine if endocrine toxicity generates the lowest endpoint within a taxon, and secondly if it is the lowest endpoint compared to that of other taxa living in the same compartment.
In the interim, however, we suggest that a compromise might be to use the lowest endpoint values estimated by the present models as shown in Fig. 5 and perhaps Fig. 6, to serve as targets for filariasis elimination.
Significant dose associations were identified for fasting high-density lipoprotein (HDL) cholesterol normal at baseline to low at endpoint and fasting triglycerides normal at baseline to high at endpoint, the incidence of which increased with increasing dose.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com