Cluster analysis also split low disease and diseased samples into different clades, with sample DT (labeled T in Figure 2), the least diseased sample based on caries outcome in the Cognitive study, splitting to the low disease clade.
Use of these medications often results in remission, or at least low disease activity (LDA), but at a substantial cost.
Affected youth report poorer HRQOL than their peers even in the setting of low disease activity and treatment with biologic disease modifying agents [4, 5, 6].
DMARDs are recommended as monotherapy for patients with early RA in remission or with low disease activity or as combinational therapy in patients with established RA [14].
However, due to the complexity of the breast structure, low disease prevalence (approximately 0.5%% [3]), and radiologist fatigue, abnormalities are often ignored.
These results help to explain the often low disease resistance heritabilities observed under field conditions.
By comparison, Hawaii has relatively low disease rates - with the exception of Wailuku, E(s) = 0.77.
In both cases, high diversity is correlated with low disease risk or prevalence.
Furthermore, by virtue of their persistence in the species, common variants are expected to have low disease penetrances.
We used the opportunistic reports to define regions of High, Intermediate and Low disease incidence (Fig. 4).
Finally, we approach a state where we detect periods of low disease prevalence interspersed with semi-regular epidemic outbreaks.
