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The low count statistics and high randoms fraction for 90Y PET imaging are likely the cause of lower count recovery compared to higher statistics 18F PET imaging.
In addition, sensitivity with Ra-223 is poor due to limited injected radioactivity (at most 10 MBq), leading to the low count statistics.
Optimized image reconstruction algorithms, with extremely low count statistics and high random counts, have yet to be resolved [20, 23, 30].
In patient data, the use of 16 bins gating is usually limited by low count statistics of the SPECT projections that appears as poor image quality.
As IQ-SPECT has a high sensitivity, it should be possible to overcome the low count statistics and improve the volume assessment accuracy.
The scans that do not benefit from gating, because they contain no motion, erratic motion, or low count statistics, can be processed and automatically reverted back to their ungated (i.e., optimal) embodiment.
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The drift and temperature numbers at high altitudes have large error bars due to low counting statistics.
Performing acquisitions over more than 60 min to probe whether the increases eventually leveled off was not possible due to the low counting statistics after three times the half-life of the radionuclide.
From the regression analysis, it resulted b = − 0.54 ± 0.07 (with r 2 = 0.86), indicating that the homogeneity index is representative of image noise (thereby associated with low counting statistics) and it is likely to decrease in proportion to the square root of the number of emitted positrons.
When count statistics are low in an imaging dataset, residual scatter counts may remain in regions of cold (i.e., no) activity, and the data supports this theory.
It should be noted that in dynamic imaging a higher level of noise is likely to be obtained due to short frame times (potentially as short as 5 10 s depending on the imaging protocol), and low noise here indicates good count statistics only.
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