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Low copy numbers are associated with higher risk of prostate cancer [23, 24].
$ORR = 0.15 was calculated when the low copy number in case was defined as 1.
These impediments include low copy number, heterogeneity, polydispersity, hydrophobicity, and intrinsic disorder.
These frequencies were plotted logarithmically on a genomic scale to distinguish regions of high TE content from low copy regions.
DPCR is capable of absolute quantification of very low copy numbers of DNA based on the high-throughput microarray chips.
Prevention of co-infection can therefore enhance the stability of low copy numbers.
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PCR targets with low copy-number (≤ 30%) could not be detected with direct sequencing.
Applications to low-copy transcripts in human samples are demonstrated.
Therefore, one would have to limit this analysis to low-copy genes.
Low-copy nuclear genes (LCNGs) have complex genetic architectures and evolutionary dynamics.
Samples containing low-copy numbers of DNA are routinely encountered in casework.
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