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3 6 Antioestrogenic effects of CC on the endometrium and cervix mucus are thought to cause the low conception rate.
This study strictly examines gene expression between high and low conception rate animals without influence from any exogenous metabolites, either dietary or pharmaceutical.
However, in the bitch herpesvirus infection has been associated with reproductive problems, such as low conception rate, fetal resorption, abortion, stillborn or weak puppies and small litter size both in experimental [ 8, 9] and epidemiological studies [ 10- 12].
Domestic buffalo are considered to have low reproductive efficiency, characterised by late attainment of puberty and maturity, seasonality of calving, long postpartum anoestrus, poor expression of oestrus signs, low conception rate and long calving intervals [ 1, 2].
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Hence, low conception rates could be directly linked to inflammation induced, altered cellular plasticity, in uterine endometrial tissues.
As high progesterone levels are positively associated with embryo survival [ 60, 93], it is therefore possible that the LF animals are experiencing low local progesterone concentrations and ultimately, this could be contributing to their low conception rates.
It was essential to use RNA from all endometrial cell types as it is not apparent, as of yet, whether or which individual endometrial cell types are contributing to low conception rates in cattle.
The north-east also had the lowest conception rate for all those between 15 and 44, at 70.6 conceptions per 1,000, while London had the highest overall conception rate at 85.2.
According to Swedish AI statistics there is a clear seasonal variation in 56 days non return rates with the lowest conception rates in January and the highest in August.
Office for National Statistics figures released in February showed that the UK under-18 conception rate remains the lowest since 1969, at 27.9 per 1,000 women aged 15 to 17.
Surgical reversal of vasectomy is somewhat more successful, achieving success about 80 percent of the time, but the conception rate following such reversal remains low.
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