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For the fluorescence quenching system we used a 1% weight/volume solution of sodium sulfite as zero PO2 for the low calibration standard.
In this way our new, simplified approach was able to identify low calibration levels (eg, under- prediction) which could be further refined.
We used two concentrations of positive controls samples: one spiked at the mid-calibration range and one at the low calibration range.
The application of item response theory models to coded electronic patient records might potentially contribute to identifying medical codes that offer poor discrimination or low calibration.
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Group 1 are the relatively 'easy' items with low calibrations (8, 1, 4), whereas group 4 are the most 'difficult' items with the highest item calibrations (12, 3).
Initially, the lowest calibration point was chosen at or slightly above the MRL determined in ultrapure water.
We obtained the highest correlation coefficient and lowest calibration error for a kernel radius R = 55 m.
The calculated data of 0.98 µg/L was below 1.5 µg/L safeguarding the lowest calibration concentration statistically.
After comparing the calculated concentrations of all the calibration points with expected concentrations, the lowest calibration point with accuracy between 70-130% was chosen for each analyte.
Sample dilution can be applied as long as the perchlorate concentration of the injected sample does not fall below the lowest calibration standard defining the working range.
The beryllium detection limit was found to be 2 ng L-1 determined as the concentration corresponding to three times the standard deviation of 12 replicates of the lowest calibration standard (0.05 μg L-1).
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