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Against the low background in this environment, even small occupancy-associated perturbations – such as from a brief entry – were discernible.
Ceria has a low background in waste incinerators and is therefore a suitable tracer for investigating the fate of nanostructured materials.
The difference in TMP affinity for bacterial compared to mammalian DHFR suggests that a TMP radioligand would have a low background in unmodified mammalian tissues and high retention in Ec dhfr engineered cells, providing high contrast imaging.
Given the low background in this study, these results stood out even if they did not reach our threshold.
Also, Tet (5 µg/ml) induced significant expression of β-catenin-ERα with very low background in non-Tet exposed cells.
In mouse tumor models, radiolabeled versions of these integrin-binding knottin peptides exhibited high tumor uptake with low background in non-target tissue (i.e. liver and kidney) [22], [23].
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How do the properties of gain controls at low backgrounds in primate retina relate to human behavioral threshold verses intensity (TVI) measurements in humans?
Intravenously injected radiolabelled nanobodies have a specific biodistribution characterised by a high renal excretion, in combination with a low background signal in other organs such as the liver, lungs and myocardium.
They also reported that seasonal variations in the nighttime TEC reveal semiannual periodicity with high background levels observed in the equinoctial months and low background levels in solstice over the Kenyan regions.
The expression of the HCNR at 81675 was almost completely confined to the developing ear, with low background expression in the branchial arch and the eye in Xenopus embryos (Fig. 2a, b).
In particular, they have wide potential window, low background current in indifferent electrolytes (KCl, K2SO4) and good reproducibility.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com