Your English writing platform
Discover LudwigSuggestions(1)
Exact(3)
As seen in Figure 4a, Bowtie1 can exhibit very low alignment rates for these samples.
The low alignment rates of Bowtie1 means that methods have available only a tiny fraction of the useful data, leading to less accurate results.
Other possible causes for low alignment rates could be misinterpretation of modified nucleosides by the sequencer or RNA editing of sequences prior to packaging into exosomes, making it difficult to compare our transcriptomic data with the available reference genomes derived from DNA sequencing.
Similar(57)
Alignment of spliced reads is more difficult than for unspliced reads and leads to lower proportions of the starting libraries being aligned, but this alone is unlikely to account for the relatively low alignment rate.
This relatively low alignment rate is an intrinsic characteristic of SOLiD 4 System sequencing [ 20].
In these tables, we report the very low alignment rate of Bowtie2, which is at most about 13%.
We focused on these subsets because of the low alignment rate on relatively short sequences, as reported in Figure 3.
The comparatively low alignment rate especially in case of the L. braziliensis library is likely a result of incomplete assembly of the reference genome or the fact that we used a different L. braziliensis strain (a clinical isolate from the Peruvian Amazon region) than the strain used to generate the reference genome.
These results exhibit a very low response alignment rate compared to males.
Surprisingly, the final library yields were very low and the results obtained from sequencing of these libraries were not satisfactory: high duplication rates coupled to low alignment percentages suggested an insufficient library complexity.
Low Alignment and low Impact e.g.g
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com