Sentence examples for low alignment from inspiring English sources

This result suggests that there were some reads that Bowtie2 could not align or gave a low alignment score when the combined reference strategy was used, which were likely reads with highly similar sequences in the human and mouse genomes.

Sampled sequences are aligned using MUSCLE [ 44], sequences with low alignment quality were manually removed.

Sequences from all samples were aligned together using SSU-ALIGN 0.1 (http://selab.janelia.org/software/ssu-align) and masked to remove inserted columns (which do not contain aligned nucleotides) as well as regions of low alignment confidence, which were determined by the calculation of posterior probabilities based on alignment to a covariance model.

Reads failing to be unambiguously aligned to a unique location would be marked as having low alignment quality, which would in turn affect the ability to identify any genetic variants it contains.

Alignment of spliced reads is more difficult than for unspliced reads and leads to lower proportions of the starting libraries being aligned, but this alone is unlikely to account for the relatively low alignment rate.

Reads that aligned to more than one region of the reference genome, reads with low alignment scores, and bases with low-quality scores were excluded from variant calling.

To filter out the inflation from the random hits of hypothetical peptides we used two of their unique alignment behaviors, namely, their very low per-peptide hits (which ranges predominantly from 0 to 10 (Additional file 1: Figure S43 45)) and the low alignment-identity profiles from their best hits (median identity value of peptides from Test case 2 was ~55 % (Fig.  4)).

From this table, the proposed system exhibits the lowest alignment error than other systems.

Each ORF was translated and searched against the Protein Data Bank (PDB) [ 55] using the PSI-BLAST algorithm [ 56] and then paired with the structural chain with the lowest alignment E-value.

For a node A i in the template DAG, the amount of free columns f i to the right of it is defined as the difference between its alignment position and the lowest alignment position of its immediate successor nodes minus one.

Likely reasons for the corresponding low-alignment scores in the present study are the presence of a SD at the 5p15.1 BP (rearrangement 8) and a LTR repeat at the 5p14.2 BP (rearrangement 10) (Supplementary Table 3).