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Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine.
That part of the molecule facing the cytoplasm has a high affinity for Na+ and a low affinity for K+, while that part facing the outside has a high affinity for K+ and a low affinity for Na+.
The purified enzyme shows unusual kinetics with a low affinity for both substrates.
Some of them showed medium to low affinity for the BDZ-bs.
Indeed, the CLG peptide presents low affinity for HLA-A2 and does not produce stable complexes.
The isolated EGF(A) domain is a poor antagonist due to its low affinity for PCSK9.
Mouse anti-human β1 integrin monoclonal 4B4 (10 μg ml−1), which recognizes receptors with low affinity for ligand (termed 'inactive'), was obtained from Beckman Coulter.
Most cells are selectively adhered on micro-structured silica particles, while a flat surface has low affinity for the cells.
This inhibitor has low affinity for human renin yet binds very tightly to the yeast proteinase (Ki=4 nM).
The magnitude of the reward attenuation induced by quetiapine is consistent with its low affinity for dopamine receptors.
Yet, both radiometabolites of 18F-MK-9470 have an extremely low affinity for CB1R.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com