Sentence examples for low activity experiments from inspiring English sources

It is not clear what fraction of Leu3 is in an activated state under the growth conditions used in the low activity experiments.

We refer to these experiments as "low activity" experiments because both involve Leu3 expressed at endogenous levels.

However, high activity ChIP and expression experiments, either by themselves or in combination with the low activity experiments, identify additional targets.

To verify this assumption, we first tested the idea on the nine bound and regulated genes identified in the low activity experiments and evaluated the Leu3 binding potential of their promoters compared to all other genes in the genome.

Of 25 genes whose upstream regions are bound by Leu3 in the low activity experiments (p ≤ 1e-3), we observed binding of 24 at high activity (p ≤ 1e-4).

The enrichment of binding potential in these genes is lower than for the genes identified in the low activity experiment, but this is expected because the genes bound at low Leu3 concentration are more likely to have more and better Leu3 binding sites than the genes bound at high Leu3 concentrations.

More importantly, there are many additional genes that are bound at the same high level of statistical confidence that are not bound in the low activity ChIP experiment.

During the low and high activity experiments the toads were instrumented with an accelerometry and temperature data logger.

The same data used to derive a regression equation (i.e. V˙o2 and ODBA during the low and high activity experiments) can be reasonably employed to validate that equation using a jack-knife statistical technique [16], [29].

This suggests protein misfolding and/or faulty targeting of these mutants and explains the low activity in the growth experiments with xylose and glucose.

To summarize, the combination of low activity ChIP and expression experiments identify most of the genes that are the primary physiological targets of Leu3.