Sentence examples for low activation of from inspiring English sources

Even low activation of EGFR, IGF-1R and IR saturates p70S6K activity and further stimulation of receptors has a minimal effect of p70S6K activation.

During reality monitoring tasks, schizophrenia patients make errors identifying "I made it up" items, and even during accurate performance, they show abnormally low activation of the medial prefrontal cortex (mPFC), a region that supports self-referential cognition.

Replicon cell lines that showed low activation of the GAS promoter, following IFN-γ treatment were selected by culturing in the presence of 1000 IU/ml IFN-γ (PeproTech Inc. Rocky Hill, NJ) for more than four months.

The relatively low activation of some of them (2 5 fold) as compared to the very pronounced induction of ΔNp63 (100 fold) reflected that ΔNp63 was not expressed at all before BMP-4 treatment (>35 cycles of qPCR) while mRNA of these genes were already detected before (22 25 cycles).

Another explanation for the strong induction of CD8+ T cell responses with very low activation of CD4+ T cells would be the induced secretion of cytokines by MVA-infected MDDC as Type I IFN [83], IL-7 [58] and IL-12 [65], [65].

Indeed, we detected low levels of CCDC6 and confirmed a very low activation of DDR-controlling molecules in the testicular germ cells tumours that we analyzed.

A D-PHI-formulated polyurethane substrate with subtle changes in anionic and hydrophobic domain content relative to the polar non-ionic urethane/carbonate groups within the polymer matrix promoted the lowest activation of monocytes, in the presence of multi-layer Fn constructs.

Similarly, medulloblastoma had the highest activation of EZH2 and lowest activation of HDAC4 in the GSK dataset but this was not completely replicated in the CCLE.

By applying these signatures to data from cancer cell lines and tumors in large public repositories, we identify those cancers that have the highest and lowest activation of each of these pathways.

Furthermore, in interpreting the main effect of expertise, which is characterized by lowest activation of the STG bilaterally in AP and highest activations in NM, it might be useful to recall the characteristic morphological lateralization of Heschl's Gyrus (Schneider et al. 2005) in professional musicians and the PT in professional musicians with AP (Schlaug et al. 1995; Keenan et al. 2001).

Further, comparing this with the HSP expression data, an inverse correlation becomes apparent: culture D.HS-2 also shows the lowest activation of the cytosolic HSP70 isoforms, thus indicating that this culture was only undergoing a moderate heat-shock but shows the lowest reduction of SAg 51D transcripts.