Sentence examples for lost responsiveness from inspiring English sources

To confirm whether Wx b in T65 had completely lost responsiveness to sucrose, we investigated the change in expression of Wx b and Wx a as sucrose levels varied from 0 to 300 mM.

Worms adapted with 1 µL of 1/10 or undiluted cyclohexanone completely lost responsiveness to cyclohexanone at 1∶100 (Figure 4).

Overall, this study showed that differentiating mouse ESCs passed through specific 'temporal windows' in which cells gained and lost responsiveness to particular factors.

The results of cell proliferation demonstrated that cells with the SENP3 C243S mutant lost responsiveness to ROS-induced proliferation.

Moreover, the hFFA2-C4.57G/H6.55Q muthat that we generated acts as a RASSL form of this receptor because it has also lost responsiveness to endogenously produced activators.

In the Phase 3 trials, a subset of the patients lost responsiveness within 3 4 months of treatment and this loss was associated with high titers of anti-pegloticase antibodies.

Many cell types lose responsiveness to anabolic factors during inflammation and disease.

In the future, engineered diets that restrict deleterious components but supplement beneficial nutrients could be used to modify the luminal intestinal environment of patients with IBD; these might be used alone or in combination with immunosuppressive agents, or as salvage therapy for patients who do not respond or lose responsiveness to medical therapies.

When this receptor is blocked, the central nervous system begins to lose responsiveness.

The cellular and biochemical mechanisms that regulate how metastatic carcinomas lose responsiveness to anoikis remain poorly defined.

However, after crossing, these growth cones lose responsiveness to netrins [4] and become sensitive to repellents made by midline cells, which include Slit proteins [5] [7].