Sentence examples for lost function as from inspiring English sources

No WBLH1 constructs lacking either the SKY, BEL or homeodomains lost function as a transcriptional activator.

These results are highly consistent with our ISOI results, and serve as additional confirmation that the cortices of +3 h rats lose function as a result of ischemic injury, while the cortices of +0 h rats are protected from ischemic injury and indistinguishable from controls.

Furthermore, these approaches do not take account of intra-species diversity (where organisms may gain or lose function as they adapt to a specific environment) or situations where organisms may be actively engaged in only a subset of their functional repertoire.

It could have turned out that everybody just lost function equally as they got older.

The first part of the lost function act as regularization preventing the QRNN from from overfitting.

As maspin has been proved a regulation target of gene p53 [ 32, 33] and maspin expression is either negative related to p53 expression or increased with the step-up of abnormal expression of it [ 34], maspin may be the replacement or supplement for insufficient or even lost function of anti-oncogene p53 as a secondary tumor suppressor gene.

With this in mind our laboratory, over last two decades, has been searching for a non-pharmacologic alternative to manage pain and restore lost function associated with acute, subacute and chronic stages of various injuries and conditions, as well as pain and lost function associated with postoperative recovery and rehabilitation.

Another type is defective viruses that lost functions to activate cellular proteins such as a tumor suppressor.

Thus, gene trapping can produce gene variants (i.e., alleles) that entirely lose their function as well as a variety of other experimental alleles if newer gene-trap vectors are used that allow for modification of expression after the insertion.

As a result, rapamycin derivatives (rapalogues) that block mTOR/Raptor complex 1 were shown to exert direct antiproliferative effects against endometrial cancers, in which cancer cells frequently lose PTEN function as well as mantle cell lymphomas, in which cancer cell proliferation appears to be driven primarily by cyclin D1 overexpression.

Human hepatitis viruses exploit multiple hepatocyte pathways during their life cycle; however, primary hepatocytes dramatically lose function and die when cultured as a monolayer in vitro.