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Gene modification of chondrocytes may be one approach to redirect cells to their primary phenotype and recent advances in nonviral and viral gene delivery technologies have enabled the expression of these lost factors at high efficiency and specificity to regain chondrocyte function.
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As it is obvious from the figure, the numbers of the resonant points and their heights decrease by the increase of the losing factors.
For four different values of the losing factor v ′ Open image in new window.
As it is observed from Table 1, these upper limits reduce by the increase of the losing factor v ′ Open image in new window.
Also, it is observed that by the increase of the losing factor, the transmission resonances slightly shift toward the lower values of the dielectric layer and the overdense plasma widths.
For the overdense plasma without dispersion, the transmission curve reaches to the maximum |T/E0|2 ≈ 1, but this maximum value decreases by the increase of the losing factor v ′ Open image in new window; so, for v ′ = 0.03 Open image in new window, it is reduced to |T/E0|2 ≈ 0.852.
It was observed that by the increase of the losing factor of the overdense plasma, the maximum of the transmission rate resonant reduces in both mechanisms, but this reduction in the case of the coupled plasmons, is remarkably lower than that in the single plasmon case.
As a result, the group of lost transcription factor gene expressions included, for example, HOXB7, HOXA9, HOXA10, PAX8, DSCR1, MYC in AFiPSCs and EMX2, FOXF2, FOXF1, MYC, KLF4 in FiPSCs.
Lineages that lack entire tethering complexes likely lost these factors as a result of selective pressure.
It has been suggested that the non-haemolytic M. ruminalis have lost virulence factors associated with their pathogenic and phylogenetic ancestors [ 23].
Therefore, the US strain of L. infantum that is circulating in North American hunting hounds has not lost virulence factors that facilitate adherence to sandfly gut and facilitate transmission, and subsequent dissemination, in a secondary host.
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