Sentence examples for lost binding from inspiring English sources

This epitope does not possess the canonical anchor residue at p5 and, as briefly discussed in the original reference, peptides may occasionally bind without primary anchor residues if other residues within the peptide compensate the lost binding energy [29].

All three variants almost completely lost binding with Sre1 when tested in the pull-down assay.

The corresponding EGFP-immunoprecipitation experiments revealed that all mutants except for M3 completely lost binding to PB3.

A lost binding site may have been replaced with a new, species-specific binding site - i.e. binding site turnover.

Genes expressed at lower levels gradually lost binding of histones modified at lysine 4 and RNA Pol II.

Therefore, viruses isolated from an airborne contact ferret did not acquire new binding specificities but merely lost binding specificities for sialic acids with α2,3 linkages.

An inverse relationship has also been observed between TCR avidity and degeneracy, indicating that as TCR gain flexibility and an increasing ability to bind different ligands they also lose binding affinity [35], [36].

Furthermore, Variant FS retains full FcRn and partial FcγRIa binding function but loses binding to FcγRII and FcγRIII receptors (Table 1 and Table 2).

We used the drkEOA mutant, which loses binding to EGFR caused by mutation in the SH2 domain [39], for a genetic interaction assay.

In common with these receptors, both bovine and human mincle lose binding activity at low pH.

First, proteins are fundamentally problematic in that they may easily lose binding activity.