Exact(2)
The VMM39 melanoma cells remained adherent five days after gamma-irradiation, but all cells had lost adherence by five days after UV-irradiation, consistent with induction of apoptosis in the vast majority of tumor cells.
They caused retraction and rounding of cultured cells, which lost adherence from their supports, while F-actin and vimentin filaments disappeared as an organized cytoplasmic network.
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After implementing the process optimization, 77% of the process activities were eliminated (104 out of 135 activities) without losing adherence to CMMI level 3 practices.
This creates a considerable shrinkage force against the crowded basal cell layer, which is forced to lose adherence to the dermal extracellular matrix (ECM).
Transient expression of MAVS protein causes HEK293T cells to crenate and lose adherence, suggesting that MAVS is cytotoxic (Fig. 1A).
During EMT cells lose adherence and tight junctions, exhibit changes in their cytoskeletal architecture, and they can break through the basal membrane and become metastatic [14].
However, as cells enter apoptosis they lose adherence and detach from the well.
Macrosopical adhesion score (6 months time point only); quantification of the adherence between device and cortex: 0 = no adherence, 1 = lose adherence, 2 = considerable adherence.
Due to the increased uptake of liposomes A and C, leading to highly fluorescent cells with high concentrations of liposomes losing adherence and reducing cell viability, liposomes A and C were not used for MRI analysis.
Liposomes A and C had the highest uptake; however, highly fluorescent cells were seen to round at high doses losing adherence and reducing cell viability at high concentration (1 m m and 0.5 m m) in both cases (Supplementary Data, Fig. S7).
While germ tubes of wild type and eed1Δ cells adhered to the plastic surface, budding filaments almost completely lost their adherence properties and yeast cells were released from the surfaces (Supplemental movies S1 and S2).
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