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The loss of variance came primarily from inbreeding.
Also a minimal loss of variance due to blocking is observed (geometric mean of efficiencies: 0.998).
The Bulmer effect was responsible for 50%% of the loss of variance, while changes in allele frequencies due to inbreeding and selection were responsible for 37.5, and 12.5 % of the loss of variance, respectively.
This implies a loss of variance in outcome measures so that associations in the regression analysis might have been underestimated.
This implies both a less validated measure of premorbid adjustment and a subsequent loss of variance in statistical analysis.
Three tSNPs were sufficient to tag the groups (R1, R3, and R10), although R5 could replace R1 and R6 could replace R3 with no loss of variance explained.
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In our preliminary analysis, we identified statistically significant relationships between subspecific Tek alleles and the initial onset of weight loss [analysis of variance (ANOVA), F2,31 = 5.581, P = 0.0085], average day of death (ANOVA, F2,34 = 10.519, P = 0.00028), and mortality (ANOVA, F2,37 = 8.5553, P = 0.0008) (fig. S9).
Loss of genetic variance and/or loss of LD between markers and QTL could be responsible.
PCA provides a linear dimensionality reduction with minimal loss of data variance.
The most immediate cause of the plateau reached by UGS is the loss of genetic variance in UGS populations.
Terms were dropped from models when their exclusion failed to generate a significant loss of model variance.
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