Sentence examples for loss of selection from inspiring English sources

We propose that this loss of selection pressure on epitope precursors is one of the main factors that determine the eventual degree of adaptation to epitope precursors that HIV-1 can reach on the population level (Fig. 5).

Consequently, pseudogenization of the UGT1A6 gene may reflect the loss of selection pressure as an ancestral felid species transitioned from a generalized (plant and animal) to a more specialized (animal only) diet [15].

The HLA-association analysis presented above (Tables 1,2 and 3) revealed that in patients with low CD4 counts HLA B*57/*5801 was associated with persistence of T242N in the TW10 epitope, whereas HLA B*8101 was associated with a potential loss of selection pressure reflected by the decreased prevalence of T186S mutants in the TL9 epitope.

This is consistent with a loss of selection in the 3' UTR that was previously maintained as coding sequence.

Because of the high selection pressure on trait 2, a small loss of selection response was observed for trait 1.

Coding sequence evolution in PHYA2 was significantly elevated, suggesting loss of selection for function, or incipient subfunctionalization.

Retaining those alleles would be difficult and would likely cause unwarranted losses of selection gain.

These adaptive changes of cellular structures can include positive selection, relaxed negative selection, and loss of negative selection at gene levels.

Yet, our results are not able to distinguish between these different forms of selection, but rather distinguish them from patterns that can be explained by population structure, loss of selective constraint, and selection on adjacent genes.

Chief among such pitfalls is the loss of randomized selection of individuals for experimental study.

Deviation of these parameters from optimal values first leads to loss of positive selection.