Sentence examples for loss of repeat from inspiring English sources
During DNA replication, the formation of insertion/deletion loops within microsatellite sequences leads to a gain or loss of repeat units (22).
Loss of the RAD27 pathway causes an increase in stationary phase minisatellite alterations, which include both gain and loss of repeat units.
Repeat expansions in these genes require the previous loss of repeat interruptions, which are thought to inhibit inter-strand slippage and to suppress intra-strand interaction [ 7, 19].
The predominant mutation mechanism in microsatellite tracts is 'slipped strand mispairing', which generates the polymorphism with regard to the gain or loss of repeat motifs [ 6].
Such a pattern may be expected, given that genome size increase by polyploidy is sudden and fundamentally different than other types of genome size variation such as the gradual accumulation or loss of repeat elements over time.
All unique alleles differing by gain or loss of repeat units were given allele numbers, thus PCR amplicons of a VNTR locus with the same size in different isolates were given the same number in table 4 [see Additional file 4].
However, a strong reduction in repeat number was observed in mammalian Xinα proteins, suggesting that this duplicated gene may have acquired a new function in mammals that is correlated with the loss of repeats in the coding region.
The morphological changes in the heart cannot be a plausible explanation for the loss of Xinβ in the avian lineage or the loss of repeats in the mammal Xinα.
LRR units probably evolve not only by nucleotide substitution but also by birth and loss of repeats following recombination events.
Repeat homeostasis of rDNA is measured by determining the repeat length of the native array, which reveals either gain or loss of repeats.
It does not seem possible, based on the analysis of a single genome as reported here, to determine whether the low repeat content of Tichoplax is due to low repeats in the eukaryotic ancestor or secondary loss of repeats and genome streamlining over time.
