The latter (loss of WT) is quorum collapse i.e. the community falls back into a halted, stagnating phase, even though the nutrients are still in place.
Well-known examples of this diversification process include conversion to the mucoid phenotype [1], [7], loss of the O antigen [8], inactivation of quorum sensing functions [6], [9], [10], loss of motility [11], [12], auxotrophies [13], resistance to antibiotics [14], and a rise in the mutation rate leading to a hypermutator phenotype.
Related to this, in two previous recent works, we showed in vitro that the MRS loss-of-function was a key determinant in targeting mucA for mucoid conversion and lasR for quorum sensing deficiency [30] [32].
Although quorum sensing is common among bacteria, the precise sensing system and class of quorum-sensing compounds used may differ.
JPMCoin, in contrast, is going to be a part of Quorum, a permissioned blockchain technology.
This strain displays phenotypes that have been associated with chronic respiratory infections in CF including alginate over-production, rough lipopolysaccharide, quorum-sensing deficiency, loss of motility, decreased protease secretion, and hypermutation.
Impeachment and removal requires a 3/4 vote of quorum.
But it is still very early in the life of quorum sensing.
But the board fell out of quorum early last year, leaving one remaining member.
