Sentence examples for loss of gene expression from inspiring English sources
Depending on the method used, loss of gene expression may be transient or sustained, enabling a wide range of functions to be investigated.
Since not all potential siRNA sequences are effective, it is also important to verify the loss of gene expression by measuring the level of channel protein remaining.
To determine whether the host adaptive immune response against the intracellular transgene human ASS (hASS) contributed to loss of gene expression in this setting, the same vector (FGV-CAG-hASS) was injected into Rag−/− (immunodeficient) mice.
Epigenetic alterations cause gene silencing, leading to loss of gene expression and function.
In addition, hypermethylation of gene promoters and the corresponding loss of gene expression are now recognized as a hallmark of human cancer [11].
The frequent copy number losses of 9p and 10q in our cohort of tumors directed our investigation into the loss of gene expression of key tumor suppressor genes found in these two regions.
The long march utilizes repeated cycles of Type IIS restriction enzyme cleavage and adapter ligation to allow extended sequencing of each library amplicon without loss of gene expression information.
Gene subsets were identified that correlated hyper (and hypo) methylation with the loss (or gain) of gene expression and in parallel, with gene dosage losses and gains, respectively.
The importance of the fine regulation of this gene and the biphasic nature of BD makes a compelling argument for the existence of genetically determined pathological switch mechanisms, which may manifest themselves in the loss of control of gene expression.
The biphasic nature of BP makes a compelling argument for the existence of genetically determined pathological switch mechanisms that may manifest themselves in the loss of control of gene expression.
The use of a simple genetic model such as Drosophila allows the examination of the cellular and organismal response to loss of Pex1 in terms of gene expression.
