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Truog and Robinson13 have pointed out that 'The most compelling justification for considering 'brain-dead' patients as being dead, is based on the notion that death is the irreversible loss of functioning of the organism as a whole.
According to the organismic definition, death is the irreversible loss of functioning of the organism as a whole (Becker 1975; Bernat, Culver, and Gert 1981).
Similar(58)
Cardiac mesoderm-specific loss-of-function of YY1 resulted in early embryonic lethality.
Surprisingly, both overexpression and loss-of-function of Nap1l3 produce similar phenotypes in primitive haematopoietic and differentiated cells.
We monitored the effect of loss-of-function of cytosolic, mitochondrial, and ER chaperones, each involved in protein input into different organelles, as well as protein folding.
Francisco Sànchez-Rivera et al. show that loss-of-function of several known tumour suppressor genes cooperates with other genetic alterations in promoting the development of lung cancer.
While loss-of-function of these signaling pathways leads to congenital malformation, the consequences of cardiac progenitor cell (CPC) or embryonic cardiomyocyte loss are less clear.
Loss-of function of FBL17 impairs PMII resulting in bicellular pollen.
Loss-of-function of LIF2 modifies flowering time, floral developmental homeostasis and gynoecium growth determination.
Loss-of-function of dRecQ4 leads to a failure of proper DNA replication and inappropriate cell cycle progression.
Loss-of function of a bilin lyase leads to a variety of effects in phycobilisome structure.
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CEO of Professional Science Editing for Scientists @ prosciediting.com