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Extended Data Fig. 5 Loss of function of PEAR genes.
AS results from the loss of function of the UBE3A gene, a gene housed within this region.
"Irreversible loss of function of the organism as a whole" became an accepted clinical criterion of death.
Prause, J. et al. Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis.
Background In X-linked adrenoleukodystrophy, mutations in ABCD1 lead to loss of function of the ALD protein.
von Hippel-Lindau (VHL) disease is caused by loss of function of the VHL tumor suppressor protein.
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Loss-of function of FBL17 impairs PMII resulting in bicellular pollen.
Loss-of function of a bilin lyase leads to a variety of effects in phycobilisome structure.
Cardiac mesoderm-specific loss-of-function of YY1 resulted in early embryonic lethality.
Surprisingly, both overexpression and loss-of-function of Nap1l3 produce similar phenotypes in primitive haematopoietic and differentiated cells.
Loss-of-function of LIF2 modifies flowering time, floral developmental homeostasis and gynoecium growth determination.
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