Sentence examples for loss of effect from inspiring English sources

In daily practice they appear to be generally effective and safe, with no evidence of loss of effect with time in the majority of patients.

However, limited by the small number of patients in this study, we can not assert whether the method works less effectively in intense pain states, or, if the loss of effect is related to the diseases' origin, or, to some other factor.

However, Dr. Lange said that "there is no reason to believe that this loss of effect is specific for" the combination of AZT and 3TC.

If a portion of Act IV could be interchanged with a portion of Act II without loss of effect, the principle of development has not been observed, for then the material occurring in between would not have made any difference.

We tested four models; in model I, we tested the purely cumulative effect, and in models II to IV, the decay function implied a 25%, 50 % and 75 loss of effect per year, respectively.

Studies in Arabidopsis and rice (Malmberg et al. 2005; Mei et al. 2005; Wang et al. 2011) have suggested that epistatic QTL effects are more important than additive QTL effects for fitness traits, for example, the loss of effect of the Saltol region in the introgression process to develop near-isogenic lines (NILs) (Thomson et al. 2010).

A second pulse at day 4 was less efficient in delaying S-phase progression, especially in PROb cells, showing a progressive loss of effects.

Different from intron gain, intron loss should be rather rare event as purifying selection always prevents its loss-of-function effect, such as what may happen to IILs.

After death of manganese labelled cells, Mn2+ diffuses passively out of these cells resulting in reduced T1-shortening effect and loss of contrast effect [ 23, 36].

This loss-of-function effect was confirmed by measuring the secretion of endogenous mediators in supernatants of HEK 293T cells (n = 3, p<0.0001; Fig. 4C).

This may be due to a partial loss-of-function effect of the two Medea RNAi constructs tested in this study, or to Medea-independent functions of Mad.