OT is characterized by several physiological, biological, and psychological symptoms with the most obvious ones being (a) a consistent decrement in performance, (b) an inability to train and recover effectively, and (c) a loss of determination and mental focus [114].
Barriers to seeking support from professionals included a fear of loss of determination, stigma [ 39] and feeling "invalidated and unheard" by professionals (p. 53) [ 37].
Dysfunction of these enzymes may cause, for instance, life-threatening diseases in humans, the loss of sex determination in nematodes and embryo lethality in plants.
However, NEUROG1 can partly compensate for the loss of the determination function of MASH1 in the olfactory placode, suggesting that NEUROG1 also has the intrinsic capacities to act as a cell determinant or differentiation factor in the same tissue [ 53].
Homelessness is the end result of a whole series of events that result in diminished capacity, loss of self-determination, most often loss of employment, loss of family, isolation, poverty, and lack of self-esteem, all leading to inability to pay for housing.
Loss of self-determination was associated with feeling "overwhelmed and powerless" (p. 56) [ 37].
Women reported negative illness consequences relating to stigma, loss of self-determination and changes to relationships.
Women noted the negative consequences of their illness in relation to stigma, loss of self-determination and changes to relationships.
Fear of loss of self-determination motivated women to appear "normal" [ 32] and prevented them seeking professional support.
An earlier study [ 36], has shown that unbalanced relationships may result in experiences of powerlessness, and loss of self-determination for the persons receiving help [ 36].
Reducing women's view that service involvement will inevitably lead to a loss of self-determination is likely to enhance engagement with services.
