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Stage 5 mitochondria were extremely large and swollen, with essentially complete loss of defined structure within the mitochondrial membrane.
Electron microscopy of adult rat cardiomyocytes subjected to sI/R show a frequent loss of defined mitochondrial crista structure, with only 48% of mitochondria retaining detectable cristae.
A similar abundance of K5K8DP TECs and loss of defined cortical and medullary areas were observed in thymic sections derived from E15.5 FTOCs following 72 hrs of culture in Wnt3a conditioned medium (Fig. S2K, upper row).
Similarly, other authors have detected the loss of defined bands in IB after cure.
The images were assessed for hippocampal atrophy, loss of defined morphologic structure of hippocampus, increased T2W signal and decreased T1W signal.
In AD, in addition to neocortical and hippocampal neurodegeneration and Aβ plaque pathology, there is a selective loss of defined neuronal populations in distinct subcortical brain nuclei, including the nucleus basalis Meynert (NbM) of the cholinergic basal forebrain [ 2, 9, 70], the Edinger Westphal nucleus (EWN) [ 21, 45, 58, 59] and the locus coeruleus (LC) [ 5, 6, 16, 32, 67].
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General solicited adverse events included fever (defined as an axillary temperature ≥37.5°C), irritability or fussiness (defined as abnormal crying), drowsiness (defined as sleepiness or tiredness), loss of appetite (defined as eating less than usual).
During the survey period, the mean productivity loss of clinically defined early-stage LD was $411 in 1997 and $88 in 1998, and the mean productivity loss of clinically defined late-stage LD was $7,762 in 1997 and $9,108 in 1998.
Loss of consciousness, defined as the point when the patients stopped pressing the button, was immediate 40 seconds after injection.
We then identified the minimal cut sets (MCS) [22] required for the loss of a defined cell function.
Age associated thymic involution is marked by a loss of a defined CMJ, a reduction in cortical area and an increase in epithelial free areas.
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